MDS analysis as performed on the Fluidity One offers a new method to quantify protein lipid interactions, based on the change in size of the protein vs protein-lipid complex. We observe that this approach offers multiple advantages over CD for this analysis.
- Find out how MDS required 40x less sample compared to CD
- Learn how CD is less sensitive, more costly and relies on there being a secondary structure change during binding, unlike MDS
- Find out how MDS was able to provide greater insights into the precise nature of the protein-lipid interaction