Fluidity One-W Brochure

Blog06 September 2019

The role of chaperones

In this article, we look at what chaperones are, what role they play in the body and how MDS is being utilized to study them.

Blog23 August 2019

Looking at the numbers: Why protein stoichiometry matters

Accurate determination of stoichiometry for a protein complex is critical to our understanding how the complex will react to other proteins or small molecules. Here we look at how stoichiometry not only effects important viral protein-antibody interactions but also disease pathology.

Application note03 April 2019

Determination of KD of aptamer protein interactions by microfluidic diffusional sizing

Here the Fluidity One-W is used to experimentally determine the KD of two protein aptamer interactions, with results in good agreement with literature values. Importantly the technique required no calibration, complex setup or specialist sample preparation. Furthermore, the interaction is assessed without immobilising or altering either molecule beyond the addition of a standard fluorescent label.