Blog10 October 2019Webinar: Measuring affinity of difficult protein targets with MDS: Q&A session
Don't worry if you missed our webinar about measuring the affinity of challenging protein targets we have transcribed the Q&A session in this blog for your convenience. Here, Dr Devenish answers your questions about Microfluidic Diffusional Sizing and explains the advantages it has over other biophysical methods that the measure binding affinity of protein interactions.
Blog23 August 2019Looking at the numbers: Why protein stoichiometry matters
Accurate determination of stoichiometry for a protein complex is critical to our understanding how the complex will react to other proteins or small molecules. Here we look at how stoichiometry not only effects important viral protein-antibody interactions but also disease pathology.
Blog11 July 2019Understanding why GPCRs are difficult to study
In this blog post we delve into the reasons behind why elucidating GPCR structures are so important as well as why they are hard to study.
Blog08 March 2019Protein analysis techniques - a history and timeline
Proteins were discovered in the late 18th century, but analytical methods to observe them were not developed until more than 100 years later. This timeline shows when different techniques were developed.
Blog04 February 2019Protein aggregation - why it matters, and how to study it
A growing field of research is dedicated to protein aggregation, which can be useful, functional or unwanted. This article explores some of the reasons why proteins aggregate, and details the techniques available to study it.