Video20 August 2019Application note video summaries
On this page we collect short video summaries of our application notes
Video13 August 2019Conference Poster Presentations 2019
Throughout 2019 we will be attending conferences all over the world and seeking out research topics and poster presetations we really think are worth taking a look at. Check back here regularly for videos of poster presentations that present cutting edge science from around the globe.
Video12 August 2019Measuring IL2 Stability in different buffers using Microfluidic Diffusional Sizing (MDS)
In this video we look at how a commercially available human interleukin-2 is assessed by microfluidic diffusional sizing on the Fluidity One across a dilution series. The hydrodynamic radius is observed to increase with increasing concentration, in a way which suggests a monomer-trimer equilibrium with positive cooperativity is established.
Blog24 May 20195 great reads: Protein-protein interactions and disease
Here are five of our favorite recent publications, highlighting both the role of protein-protein interactions in disease and how the characterization of these interactions may allow the development of new therapeutic strategies.
Infographic15 March 2019The cost of poor quality protein
This infographic explores what is meant by "protein quality" - and where it can cause problems in research.
Blog01 March 2019The importance of pre-crystallization screening of membrane proteins - and how to do it
We investigate the importance of pre-screening membrane proteins before crystallization, with examples and comments from the literature, and take a look at 4 methods which can be used to do this.
Blog20 December 2018The role of analytics in the discovery and development of biopharmaceuticals
As the biopharmaceuticals market continues to grow, how do laboratory analysis methods support discovery and development? And what should be considered when selecting an analysis method?
Application note22 August 2018Interleukin-2 stability in changing buffer and temperature conditions
The stability of interleukin-2 in different buffers and storage temperatures is evaluated using the Fluidity One. We find that IL-2 forms aggregates within 24 hours in some buffers, and that the Fluidity One provides a simple means to evaluate the stability of proteins across different conditions.
Blog17 July 2018What biophysical attributes of biopharmaceuticals are measured, and why?
An array of characteristics must be investigated in new biopharmaceuticals to evaluate their safety, efficacy and behaviour under changing conditions. Here we look at what specific attributes should be measured and why.