Video13 August 2019Conference Poster Presentations 2019
Throughout 2019 we will be attending conferences all over the world and seeking out research topics and poster presetations we really think are worth taking a look at. Check back here regularly for videos of poster presentations that present cutting edge science from around the globe.
Video12 August 2019Measuring IL2 Stability in different buffers using Microfluidic Diffusional Sizing (MDS)
In this video we look at how a commercially available human interleukin-2 is assessed by microfluidic diffusional sizing on the Fluidity One across a dilution series. The hydrodynamic radius is observed to increase with increasing concentration, in a way which suggests a monomer-trimer equilibrium with positive cooperativity is established.
Publication01 August 2019Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis
In this paper, the authors utilise microfluidic diffusional sizing and electrophoresis to characterise the oligomeric states of the chaperone protein alphaB-crystallin.
Blog04 July 2019The Protein Society Symposium 2019 roundup
In this blog post we showcase videos of authors taking us through their poster presentations and highlight key papers from the talks from our favourite seven topics.
Infographic15 March 2019The cost of poor quality protein
This infographic explores what is meant by "protein quality" - and where it can cause problems in research.
Application note11 December 2018Quantitation of low Tryptophan and Tyrosine peptides using the Fluidity One
UV absorbance is commonly used as a fast method for protein and peptide quantitation, however samples must contain tryptophan (Trp) or tyrosine (Tyr) residues to be detected. Here we demonstrate the ability of the Fluidity One to assess the concentration of a range of samples which have low or no Trp and Tyr content.
Blog30 May 2018How does the Fluidity One compare to UV-Vis spectrophotometers in testing the concentration of proteins?
UV-vis absorbance testing is a popular method for rapid testing of protein concentration with only a small sample volume needed. Here we compare this method to Microfluidic Diffusional Sizing (MDS), as used on the Fluidity One, to see how the workflow, accuracy, test method, range and limitations compare.
Blog23 April 2018What analytical laboratory methods are available for protein quantification? How do they compare?
Quantification is an essential part of protein analysis and quality control. Here we look at the various approaches for protein quantification, their advantages, and their limitations.