Resources

Publications, application notes and more

  • Blog10 October 2019

    Drug Target Review webinar: Q&A session

    Don't worry if you missed our recent webinar with Drug Target Review, we have transcribed the Q&A session with speaker Dr Sean Devenish in this blog.

  • Blog09 October 2019

    Q&A session from BSI 2019

    Fluidic Analytics is proud to be a part of the first French congress of Structural Integrative Biology (BSI-2019), hosted at Paul Sabatier University in Toulouse. In this blog we have transcribed the Q&A part of the presentation that we gave on 8th October.

  • Blog03 October 2019

    Cancer drugs might not work the way we think they do

    The majority of proposed anticancer treatments do not succeed in advancing to clinical use because of problems with efficacy or toxicity, often for unclear reasons. Lin et al. discovered that a drug candidate in clinical development was effective at killing cancer cells even when its target protein was knocked out, suggesting that its proposed mechanism of action was incorrect

  • Blog06 September 2019

    The role of chaperones

    In this article, we look at what chaperones are, what role they play in the body and how MDS is being utilized to study them.

  • Blog23 August 2019

    Looking at the numbers: Why protein stoichiometry matters

    Accurate determination of stoichiometry for a protein complex is critical to our understanding how the complex will react to other proteins or small molecules. Here we look at how stoichiometry not only effects important viral protein-antibody interactions but also disease pathology.

  • Blog14 August 2019

    Getting to the heart of the matter: GPCRs as therapeutic targets for heart failure

    In this blog post we cover the functions of key GPCRs in the heart and how they are now being targeted for therapeutic treatments to reduce the impact of coronary heart disease

  • Blog11 July 2019

    Understanding why GPCRs are difficult to study

    In this blog post we delve into the reasons behind why elucidating GPCR structures are so important as well as why they are hard to study.

  • Blog04 July 2019

    The Protein Society Symposium 2019 roundup

    In this blog post we showcase videos of authors taking us through their poster presentations and highlight key papers from the talks from our favourite seven topics.

  • Blog03 July 2019

    Affinity vs Avidity- What's the difference?

    In this blog post we will be delving into the differences between affinity and avidity

  • Blog24 May 2019

    5 great reads: Protein-protein interactions and disease

    Here are five of our favorite recent publications, highlighting both the role of protein-protein interactions in disease and how the characterization of these interactions may allow the development of new therapeutic strategies.

  • Blog02 April 2019

    When protein-lipid interactions matter

    This blog explores some examples from the literature where the interactions of proteins and lipids have made a big impact on the overall research.

  • Blog18 March 2019

    5 exciting papers on membrane proteins

    This list gives a summary and link to 5 excellent papers which highlight some of the most recent and exciting work taking place in the field of membrane proteins.

  • Blog08 March 2019

    Protein analysis techniques - a history and timeline

    Proteins were discovered in the late 18th century, but analytical methods to observe them were not developed until more than 100 years later. This timeline shows when different techniques were developed.

  • Blog06 February 2019

    Born Slippy; Protein-Lipid interactions around the human body

    There are many proteins which interact with lipids in vivo, in complex relationships that have crucial impacts on organism health. These are often thought of as disease causing, but can also play roles in normal biochemical functions. Here are some examples of protein-lipid interactions from around the human body, which play a part in healthy activity in cells.

  • Blog04 February 2019

    Protein aggregation - why it matters, and how to study it

    A growing field of research is dedicated to protein aggregation, which can be useful, functional or unwanted. This article explores some of the reasons why proteins aggregate, and details the techniques available to study it.

  • Blog04 February 2019

    Biophysics for Biologists

    Protein X is a key suspect in causing disease Y. So how do you study protein X?

    Here we look at biophysics from a biologist's point of view; asking why is biophysics important? What can biophysics contribute to biology? And what biophysics techniques should biologists know about, and use?

  • Blog29 November 2018

    Social Network. But For Proteins

    As the $31m investment round in Fluidic Analytics is announced, Vishal Gulati of Draper Esprit reflects on how he first met the founders, why proteins matter and how our technology is set to change protein science.

  • Blog14 September 2018

    Basel Life and Miptec 2018 - poster and presentation download

    The Miptec exhibition at Basel Life 2018 marked the official launch of our Fluidity One instrument. Download a copy of our poster and presentation from the event here.

  • Blog17 July 2018

    What biophysical attributes of biopharmaceuticals are measured, and why?

    An array of characteristics must be investigated in new biopharmaceuticals to evaluate their safety, efficacy and behaviour under changing conditions. Here we look at what specific attributes should be measured and why.

  • Blog17 July 2018

    A day in the life of a Software Engineer at Fluidic Analytics

    Principal Software Engineer, Mauricio Varea, talks about his career path to date, working in large and small companies and what a typical day looks like for him at Fluidic Analytics.

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