Blog06 September 2019The role of chaperones
In this article, we look at what chaperones are, what role they play in the body and how MDS is being utilized to study them.
Blog23 August 2019Looking at the numbers: Why protein stoichiometry matters
Accurate determination of stoichiometry for a protein complex is critical to our understanding how the complex will react to other proteins or small molecules. Here we look at how stoichiometry not only effects important viral protein-antibody interactions but also disease pathology.
Publication25 July 2019Microfluidic diffusional sizing (MDS) in the literature
Document referencing all the publications where microfluidic diffusional sizing (MDS) has been used.
Infographic11 July 2019Researching therapies for Alzheimer’s Disease
In this infographic, we break down all the failures of potential therapies that were tested to treat Alzheimer's Disease. This includes a cost and percentage breakdown of the clinical phases in which these therapies failed in as well as statistics for world-wide Alzherimer's Disease epidemiology.
Blog04 July 2019The Protein Society Symposium 2019 roundup
In this blog post we showcase videos of authors taking us through their poster presentations and highlight key papers from the talks from our favourite seven topics.
Publication04 June 2019Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
In this paper MDS was used to identify two molecular chaperones which suppress secondary nucleation processes and inhibit the elongation of Aβ fibrils seen in Alzheimer's disease.
Blog24 May 20195 great reads: Protein-protein interactions and disease
Here are five of our favorite recent publications, highlighting both the role of protein-protein interactions in disease and how the characterization of these interactions may allow the development of new therapeutic strategies.
Blog04 February 2019Protein aggregation - why it matters, and how to study it
A growing field of research is dedicated to protein aggregation, which can be useful, functional or unwanted. This article explores some of the reasons why proteins aggregate, and details the techniques available to study it.
Blog17 July 2018What biophysical attributes of biopharmaceuticals are measured, and why?
An array of characteristics must be investigated in new biopharmaceuticals to evaluate their safety, efficacy and behaviour under changing conditions. Here we look at what specific attributes should be measured and why.