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Home > Menu of Standard Assays – Products > Protein Interactions Lab
What if you could measure complex protein interactions in close to in vivo conditions?
What more could you discover?
Microfluidic Diffusional Sizing (MDS) is a proprietary technology which opens the door to quantify and characterize protein interactions, regardless of background or target complexity. Utilizing MDS technology, Fluidity One systems analyze the most challenging targets, in buffers, cell lysates or serum, to deliver molecular size, affinity (KD), concentration and stoichiometric data.
The Protein Interactions Lab offers you instant access to the proprietary Fluidity One platform, developed and manufactured to our 9001 and 13485 certifications, so you can characterize and quantify protein interactions in solution.
MDS may have the answer. You won’t know until you try. Choose the Protein Interactions Lab as a go-to resource to accelerate progress – from custom protocol and assay development to routine sample testing.
Alexa Fluor™ 488 or 647 labelling, clean-up, determination of degree of labeling and QC
In-solution affinity measurements of purified proteins to other species* listed on our standard menu
Determination of serum antibody affinity and concentration*
Binary yes/no determination of neutralizing ability of serum antibodies*
Custom protocol & assay development as well as assay validation on custom samples
Comprehensive report including data analysis and guidance on possible future directions
Develop custom protocols and assays together with our experienced and dedicated scientists
Choose from a broad menu of assays for routine sample testing
Provide your own proteins or let us source and label suitable proteins for you
Receive a comprehensive data report summarizing results and observations based on our analytical expertise with protein interactions
Benefit from our seamless end-to-end project management LIMS
Protein labeling Labeling customer-provided protein with fluorophore (Alexa Fluor™ 488 or Alexa Fluor™ 647, clean-up, determination of degree of labeling, QC by Fluidity One-W). Proteins can be sourced directly on customer’s behalf at cost where third-party licence agreements permit. Note that this can be provided as a standalone service.
MAAP assay Determination of serum antibody affinity (to the targets listed on our standard assay menu) and concentration as per user guide (see SARS-CoV-2 Antibody Profiling User Guide for example).
Rapid affinity-based neutralization assay Binary yes/no determination of neutralizing ability of serum antibodies against the targets listed on our standard assay menu (see Affinity-based SARS-CoV-2 Surrogate Virus Neutralization Test for example).
KD of purified protein in buffer In-solution affinity measurement of purified protein binding to another species for proteins listed on our standard menu. For the above assays see our website for the full menu of validated targets we can offer. We are constantly expanding our menu so check back regularly.
The fastest, most convenient way to access our transformational platform for quantifying protein interactions: You send us your samples. We send you a complete data set and in-depth analysis by one of our scientific experts.
Immediate access to our rapidly expanding menu of assays including:
Bespoke assay development services to develop new versions of assays for your specific targets or completely new assays for your novel applications.
For cases where your application requires a bespoke assay, we can develop one for you. We will work together with you to establish the assay and validate it on samples of your choice.
All service contracts come with a full report as the main deliverable. The report is in-depth and includes analysis of your data by one of our experts, including insights and possible future directions. You will also receive a copy of all raw data from your samples. Long-term sample storage after work is complete can be provided if required.
Yes. An anonymized copy of all data will be kept in our system to help us improve our existing products and services and to develop new ones. We will not sell your data set or your personal data on to third parties.
Samples are routinely run in our CL2 service laboratory at Fluidic Analytics’ headquarters in Cambridge, UK. We also have a backup facility in Boston, Massachusetts, USA that can be called on when required.
Fluidic Analytics has been certified to ISO-9001 and ISO-13845.
All work will be led by our team of highly qualified staff with decades of experience working with biological samples. The scientists who will be working with you are all leading experts on Fluidic Analytics’ platform and its applications because they have helped to develop them since Day One.
(For research use only.)
Please just give us a few details about your work below and we'll be in touch to discuss the next steps in analyzing your protein interactions, even in complex backgrounds.
Get in touch, our applications scientists will be happy to discuss your application requirements with you.
