One Partner. Complete Insight.

Single-cell screening to in-solution binding analysis — one team, two product families.


A Fluidic Sciences brand

Find the cells you want, faster.

Make your decisions earlier and with precision. With Cyto-Mine® and Cyto-Mine® Chroma, you can screen millions of cells in 4-6 hours, gently, accurately and with monoclonality assurance. Hit your milestones sooner.

Fluidity One-M

from Fluidic Sciences

Move faster – from binding to findings.

Binding affinity, concentration, stoichiometry and size in solution – a full binding curve and KD in a simple 25-minute workflow.

Seamlessly traverse cellular
function and molecular binding

As the home of Sphere Bio and Fluidity One‑M, we deliver an end‑to‑end portfolio for complex biology. Move seamlessly from multiplex single‑cell screening to in‑solution biophysics – reducing assumptions and accelerating confident decisions.

Go straight to your application

What customers are saying

“Cyto-Mine® allows analysis that may once have taken weeks to finish to be completed within one day.”

Dr Fay Saunders UK Head of Upstream Mammalian Cell Culture, Process Development, FUJIFILM Biotechnologies

“We initially developed the MDS technology in our lab and have now switched to using the Fluidity One M instrument for all of our MDS and protein interaction work because it’s very robust and convenient.”

Prof. Tuomas Knowles University of Cambridge

“Cyto-Mine® plays a key role in the AbZelectPRO platform by accelerating development timelines. It enables early-phase enrichment of the pool population, thereby streamlining and reducing the duration of the subsequent clone screening process.”

Dr Brett Verstak Director of Cell Line Development, Abzena

“MDS allowed us to obtain unique information that helped us elucidate, for the first time, the way antibody therapeutics bind to different forms of their targets.”

Prof. Sara Linse Lund University

“MDS allows simultaneously determining both concentration and affinity of donor-specific antibodies under native conditions, directly in clinical samples, which is highly valuable.”

Dr Gideon Hoenger University Hospital Basel

Meet Fluidity One-M

Our toolbox to fast-track protein interaction analysis

Measure in solution

Direct measurement in solution without purification and immobilization.

Start simple

Just mix and measure, with machine learning guided assays

Break the constraints

Works for any targets and backgrounds, such as serum, plasma and cell lysate

Work faster

Get a full binding curve and KD with a simple workflow in 25 minutes

Avoid biases

With single-use consumables. No cross-contamination

Complete the picture

Binding affinity, concentration, stoichiometry and size, all at once

Driven by cutting-edge technologies

The two platforms behind our product families

FLUIDITY ONE-M · MICROFLUIDIC DIFFUSIONAL SIZING (MDS)

Size changes reveal binding

MDS gives one simple and direct measurement: protein molecular size. When binding occurs, changes in protein size are used to determine binding affinity and calibration-free concentration or binding stoichiometry.

SPHERE BIO · PICODROPLET MICROFLUIDIC TECHNOLOGY

The core of our Cyto-Mine® platforms

Each picodroplet encapsulates a single cell in a stable, biocompatible droplet with minimal leakage, right down to small molecules such as metabolites: an ultra-miniaturized test tube for large-scale, single-cell experiments. Our platforms, consumables and reagents build on this for biologics discovery and development, cell engineering and synthetic biology.

Fluidic Sciences Ltd